Chinese medicine ultra-fine grinding is with the development of modern ultra-fine powder technology and a new Chinese medicine processing technology. The fine powder of Chinese herbal medicine is pulverized to a micron level, which improves the cell wall breaking rate and specific surface area, thereby increasing the dissolution rate, bioavailability, reducing the dosage and enhancing the pharmacological action of the active ingredient. Chinese medicine industry's widespread concern.
Supersonic airflow crushing technology is one of the main means of ultra-fine grinding, which according to aerodynamic theory, the multi-nozzle technology, fluidized bed technology, vortex grading technology into one, forming a set of supersonic airflow crushing, grading system. Its working principle is to clean, dry compressed air into the specially designed nozzle to form a supersonic airflow, through several opposing nozzles into the grinding chamber, the material from the hopper to the crushing chamber by the nozzle air flow to accelerate the impact of the jet Cross-point to achieve crushing, crushing the formation of high-speed indoor two-phase flow fluid bed, powder self-collision, to achieve crushing, and then through the vortex high-speed grading machine, under the action of centrifugal force classification. Powder through the air crushing and grading, particle size can reach micron level.
Supersonic airflow crushing production operations, with a sealed, instantaneous, low temperature, physical process and so on. The entire production process is carried out in a closed system, to avoid pollution to the environment, while reducing the environmental pollution of the product. Supersonic airflow crushed, due to the rapid expansion of the air is an endothermic process, so the entire crushing space is low temperature environment, the powder is crushed at low temperature instantly completed. Thus avoiding the material in the crushing process to produce heat and damage the chemical composition of the phenomenon occurs, suitable for heat-sensitive and volatile ingredients of traditional Chinese medicine crushing. Airflow crushing is purely physical behavior, does not occur any chemical reaction, and thus can maintain the original chemical properties of the material.
Traditional Chinese medicine formula granule is a deep processing product of traditional Chinese medicine Pieces. In view of the traditional habit of using some of the traditional Chinese medicine powder, it has a good prospect for improving the quality of traditional Chinese medicine formula granules by supersonic airflow crushing technology. Jiangyin Tianjiang Pharmaceutical Co., Ltd. carried out years of exploratory research work in this area, and achieved preliminary results. Such as Sanqi, Fritillaria, Amber, Placenta, Gastrodia, Cordyceps sinensis, etc., these varieties made of ultra-fine powder, retain the whole composition, and because the cell wall rupture, All kinds of ingredients have been released state, boiled water, rapid onset, bioavailability is also higher. For some varieties with dense texture and low water extraction rate of active ingredients, such as Poria, Ganoderma lucidum, sandalwood and so on, the use of supersonic airflow crushing technology made of ultrafine powder, improve the utilization of Poria polysaccharides, Ganoderma lucidum polysaccharide, The aroma of sandalwood flavor components. Application of supersonic airflow crushing technology, but also to overcome some of the traditional varieties of traditional Chinese medicine preparation formula particles encountered technical problems encountered. Such as containing a lot of resin, gum frankincense, myrrh, with a large number of sugar medlar and other varieties, in the concentrated liquid drying process is easy to soften, sticky wall, need to add a lot of accessories to complete the drying operation, Big. The use of traditional crushing technology, due to the process of grinding a lot of heat, so that the material softened, adhere to the grinder blade and screen, can not complete the crushing operation, and supersonic airflow crushing low temperature characteristics can overcome this drawback.
Supersonic airflow crushing technology to the Chinese medicine formula particles research, production provides a new means to save and protect the resources of Chinese herbal medicines to improve the quality of drugs has a positive significance. The application of this new technology, mainly from the powder particle size, uniformity, specific surface area, cell wall rate, part of the dissolution of traditional Chinese medicine ingredients, quality standards and other aspects of research. Although the toxicity of traditional Chinese medicine has not yet seen the report of ultrafine powder, due to the large amount of ultrafine powder dissolution, so that the active ingredients and other components of the dissolution of the increase at the same time, in view of safety considerations, this technology has not been widely used in the production of traditional Chinese medicine granules The In the future to strengthen the drug safety aspects of in-depth study, to carry out ultra-fine powder and traditional water decoction dose conversion study. At present, Jiangyin Tianjiang Pharmaceutical Co., Ltd. has organized the relevant research institutes joint research, the application of supersonic airflow crushing technology to enhance the quality of Chinese medicine formula particles.